20/08/49 Bury (a) 2-0 Stephenson, Thompson
24/08/49 Everton (h) 0-1 no scorer 0-0 (EFC scorer Catterick 15)
27/08/49 Wolves (h) 1-0 Taylor
31/08/49 Everton (a) 1-1 Sibley (0-0 HT) (EFC scorer Higgins 55 for 1-0)
03/09/49 Chesterfield (a) 2-2 Sibley, Stobbart
10/09/49 Aston Villa (h) 2-2 Graver, Thompson
14/09/49 Blackburn Rovers (h) 1-2 Thompson 27 1-0 ht (BR scorers Ashworth 64, Fenton 80)
17/09/49 Manchester City (a) 3-1 Steele, Graver, Fraser pen, 1-0 HT (MC scorer Cunliffe 1-1)
24/09/49 Sheffield Wednesday (h) 2-0 Thompson, Stobbart
01/10/49 Stoke City (a) 1-2 Harbertson
08/10/49 Sheffield United (h) 2-4 E.Robledo, Harbertson
15/10/49 Manchester United (a) 0-0 no scorer
22/10/49 West Bromwich Albion (h) 1-0 Steele
29/10/49 Barnsley (a) 1-0 Hannah
05/11/49 Derby County (h) 2-0 Thompson, Steele
12/11/49 Bolton Wanderers (a) 0-1 no scorer
19/11/49 Leeds United (h) 1-0 Thompson
26/11/49 Liverpool (a) 2-0 Boyle, Graver
03/12/49 Burnley (h) 3-1 Thompson, Graver[2]
10/12/49 Preston North End (a) 1-2 Hannah
17/12/49 Bury (h) 2-0 Hannah, Taylor
24/12/49 Wolves (a) 1-3 Sibley 8 (WWFC scorers: Taylor 55, Wilshaw 61, Hancocks 88) (HT 1-2)
26/12/49 Blackpool (a) 0-0 no scorer
31/12/49 Chesterfield (h) 2-0 Graver[2]
02/01/50 Blackpool (h) 0-0 no scorer
07/01/50 Manchester United (h) 5-0 Thompson[3], Graver, Sibley
14/01/50 Aston Villa (a) 0-0 no scorer
21/01/50 Manchester City (h) 1-2 Hixon
04/02/50 Sheffield Wednesday (a) 3-0 Houghton[2], Taylor
18/02/50 Stoke City (h) 3-0 Houghton[2], Thompson
25/02/50 Sheffield United (a) 6-1 Graver[2], Steele[2], Taylor, Thompson
11/03/50 West Bromwich Albion (a) 1-0 G Robledo
18/03/50 Barnsley (h) 3-0 Milburn[2], G Robledo
25/03/50 Derby County (a) 0-0 no scorer
01/04/50 Bolton Wanderers (h) 1-1 Thompson
07/04/50 Huddersfield Town (a) 0-2 no scorer
08/04/50 Leeds United (a) 2-3 scorers tbc (LUFC scorers: Tapscott, Dudley, Moss)
10/04/50 Huddersfield Town (h) 2-0 Stokoe, Hixon
15/04/50 Liverpool (h) 0-4 no scorer
22/04/50 Burnley (a) 0-5 no scorer
29/04/50 Preston North End (h) 0-2 no scorer
06/05/50 Blackburn Rovers (a) 2-1 G Robledo, armstrong

NUFC finished in 6th place, on 49 points